PUR Biologics, LLC is a medical device company uniquely focused on the development of regenerative biologic solutions for musculoskeletal applications, including orthopedic, spine, dental and medical device indications.

From its core technology, PUR Biologics has developed a rich product portfolio that fulfills market needs without the clinical risks, disadvantages, and economic challenges of using embryonic stem cells or animal products.
  
PUR's human multipotent cell conditioned media (CCM) and extracellular matrix (ECM) materials are targeted for use in the orthopedic areas of bone, cartilage, intervertebral disc and ligament regeneration, as well as a biological coating for medical devices. A soluble composition of naturally-secreted proteins, the CCM contains growth factors such as follistatin and stem cell factor which are known to stimulate stem cell growth, differentiation, and tissue regeneration. The insoluble ECM, made up of a variety of collagens and other matrix proteins, holds promise as an excellent biologically-active filler, attracting fibroblasts and stem cells as well as supporting new tissue growth.

PUR Biologics will build upon current sales of a specialized inductive allograft product line to bring orthopedic products based on the CCM and ECM through all stages of development and into commercialization. The Company’s current research and development efforts in the area of bone regeneration have potential benefits in a number of orthopedic applications, followed with the use in device coating and intervertebral disc regeneration.
  
PUR Biologics strives to deliver the most innovative and cost effective regenerative and cellular technologies to improve lives and functionality.

Testimonials Chad Prusmack, MD - “Regenerative technologies are paramount in advancing the current state or orthopedics and neurosurgery,” said Dr. Chad Prusmack Chief of Neurosurgery at Rocky Mountain Spine Clinic and consultant to the Denver Broncos. “The use of naturally-secreted human growth factors and matrix proteins, known to stimulate and support stem cell growth in the body, can prove to be transformational in the regeneration of multiple musculoskeletal and neuronal tissues .These unique preparations may be the universal 'transducer' needed for optimizing directed stem cell differentiation and healthy proliferation." - Chad Prusmack, MD Chief of Neurosurgery - Rocky Mountain Spine Clinic - Denver Broncos Consultant

Current News 03/11/13 Press Release Histogen Creates PUR Biologics, a Joint Venture Developing Next-Generation, Biologic Solutions in Orthopedic Applications